The game begins during a zombie outbreak, referred to as "Walkers," which has overtaken the world and brought humanity to the brink of extinction. The main character is Lee Everett, a man who was sentenced to prison for murder, but he escapes from a police car on the way to prison when the zombie outbreak occurs. After escaping, Lee encounters a young girl named Clementine, who is lost and trying to survive in a world filled with dangers from both the zombies and the remaining humans. Lee takes responsibility for looking after Clementine, and the two must work together to survive in a world full of violence and sorrow. The game features important decision-making, where every choice the player makes impacts the story and the relationships between characters. These decisions can even change the course of events. The game is divided into multiple episodes, and the story gradually develops based on the player's choices.