Devil May Cry 4 begins with Nero, a Devil Hunter who works for a church called the "Order of the Sword," a group dedicated to hunting demons. The story starts when Nero witnesses Dante, the main character from the previous games, destroy the Order of the Sword's church and kill their leader. Nero then pursues Dante while facing demonic enemies and uncovering a complex story involving the secrets of the Order of the Sword and its connection to demonic powers. During his journey, Nero discovers many secrets about himself, and his quest for the truth leads to internal conflicts within the organization. He also uncovers his relationship with Dante, which ultimately forces him to make a crucial decision about his path.